Hemodynamic Stability During Severe Scoliosis Surgery Using A Dexmedetomidine-Based Anesthesia Regimen: A Case Report

Authors

  • William Wilson Wantania Universitas Sam Ratulang
  • Diana Christine Lalenoh Universitas Sam Ratulangi

DOI:

https://doi.org/10.59141/-.v8i2.540

Keywords:

Stability, Severe Scoliosis, Dexmedetomidine, Balanced Anesthesia

Abstract

Severe adult idiopathic scoliosis with a Cobb angle >80° is a complex condition that presents significant anesthetic challenges due to restrictive ventilatory impairment, potential hemodynamic instability, and the risk of massive blood loss during spinal surgery. A 20-year-old woman with an American Society of Anesthesiologists (ASA) Physical Status Classification II was diagnosed with Lenke type 3 idiopathic scoliosis (Cobb angle: 83°) and scheduled for spinal stabilization surgery. Preoperative evaluation revealed a Mallampati class II airway, preserved cardiac function (ejection fraction [EF] 62%), and restrictive pulmonary impairment with low cardiopulmonary risk. General anesthesia was administered using a combination of dexmedetomidine (0.3 mcg/kg/hour), fentanyl (3 mcg/kg), propofol (2 mg/kg), rocuronium (1 mg/kg), and desflurane (6–7 vol%). Intraoperative hemodynamic parameters remained stable. Postoperatively, the patient was successfully extubated in the operating room and transferred to the inpatient ward after 24 hours of intensive care unit (ICU) monitoring, with adequate pain control and no neurological complications. The dexmedetomidine-based anesthesia regimen provided hemodynamic stability, reduced the requirement for additional anesthetic agents, and supported early extubation without respiratory depression. A comprehensive anesthetic approach and blood conservation strategy contributed to optimal clinical outcomes. Comprehensive anesthesia management in severe scoliosis may improve physiological stability, reduce complications, and facilitate recovery.

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References

Beeton, G., Zagales, I., Elkbuli, A., et al. (2023). Cost-effectiveness of cell salvage in trauma blood transfusions. The American Surgeon, 89(11). https://doi.org/10.1177/00031348231175124

Cui, Q., Ma, T., Liu, M., Shen, Z., Li, S., Zeng, M., et al. (2023). Intraoperative infusion of dexmedetomidine for prevention of postoperative delirium in elderly patients undergoing craniotomy: A protocol of randomised clinical trial. BMJ Open, 13(1), e063976. https://doi.org/10.1136/bmjopen-2022-063976

Hatef, J., Hatef, S., Drain, J. P., Tobias, J. D., Martin, D., Shell, R., Chase, M., Beebe, A., Samora, W., & Klamar, J. (2022). Protocol-driven early tracheal extubation in patients with flaccid neuromuscular scoliosis and pre-existing lung disease. Spine Deformity, 10, 689–696. https://doi.org/10.1007/s43390-021-00411-6

Hudec, J., Prokopová, T., Kosinová, M., & Gál, R. (2023). Anesthesia and perioperative management for surgical correction of neuromuscular scoliosis in children: A narrative review. Journal of Clinical Medicine, 12(11), Article 3651. https://doi.org/10.3390/jcm12113651

Jiang, X., Tang, X., Liu, S., et al. (2023). Effects of dexmedetomidine on evoked potentials in spinal surgery under combined intravenous inhalation anesthesia: A randomized controlled trial. BMC Anesthesiology, 23, 1–10.

Jin, C., Wang, S., Yang, G., Li, E., & Liang, Z. (2022). A review of the methods on Cobb angle measurements for spinal curvature. Sensors, 22, Article 3258. https://doi.org/10.3390/s22093258

Joshi, G. P. (2021). General anesthetic techniques for enhanced recovery after surgery: Current controversies. Best Practice & Research Clinical Anaesthesiology, 35(4), 531–541.

Kundra, S., et al. (2019). Effect of a low-dose dexmedetomidine infusion on intraoperative hemodynamics, anesthetic requirements and recovery profile in patients undergoing lumbar spine surgery. Journal of Anaesthesiology Clinical Pharmacology, 35(2), 248.

Levine, S. B. B., Fields, M. W., Boby, A. Z. M., Matsumoto, H. M., Skaggs, K. F. B., Roye, B. D. M., & Vitale, M. G. M. (2022). Degree of postoperative curve correction decreases risks of postoperative pneumonia in patients undergoing both fusion and growth-friendly surgical treatment of neuromuscular scoliosis. Journal of Pediatric Orthopaedics, 42, 372–375. https://doi.org/10.1097/BPO.0000000000002155

Mahmoud, M., Barbi, E., & Mason, K. P. (2020). Dexmedetomidine: What's new for pediatrics? A narrative review. Journal of Clinical Medicine, 9(9), Article 2724. https://doi.org/10.3390/jcm9092724

Misal, U. S., Joshi, S. A., & Shaikh, M. M. (2016). Delayed recovery from anesthesia: A postgraduate educational review. Anesthesia: Essays and Researches, 10(2), 164.

Moore, D. W., & Forsthoefel, C. (2024). Blood loss management in spine surgery. Orthobullets. https://www.orthobullets.com

Pacheco, L. D., & Saad, A. F. (2024). Ventilator management in critical illness. In Critical Care Obstetrics (pp. 233–266).

Reysner, M., Kowalski, G., Geisler-Wojciechowska, A., Resyner, T., & Wieczorowska-Tobis, K. (2025). Anesthesia and pain management for scoliosis surgery: A narrative review. Clinical Spine Surgery, 38(6), 259–265. https://doi.org/10.1097/BSD.0000000000001758

Stephens, R. S., & Whitman, G. J. R. (2015). Postoperative critical care of the adult cardiac surgical patient. Part I: Routine postoperative care. Critical Care Medicine, 43(7), 1477–1497.

Weerink, M. A. S., Struys, M. M. R. F., Hannivoort, L. N., Barends, C. R. M., Absalom, A. R., & Colin, P. (2017). Clinical pharmacokinetics and pharmacodynamics of dexmedetomidine. Clinical Pharmacokinetics, 56(8), 893–913. https://doi.org/10.1007/s40262-017-0507-7

Weissmann, K. A., Lafage, V., Pitaque, C. B., Lafage, R., Huaiquilaf, C. M., Ang, B., & Schulz, R. G. (2021). Neuromuscular scoliosis: Comorbidities and complications. Asian Spine Journal, 15, 778. https://doi.org/10.31616/asj.2020.0263

Wishart, B. D., & Kivlehan, E. (2021). Neuromuscular scoliosis: When, who, why and outcomes. Physical Medicine and Rehabilitation Clinics of North America, 32, 547–556. https://doi.org/10.1016/j.pmr.2021.02.007

Zhang, Q., Zhang, Z., Wang, B., Zhao, C., & Xu, Y. (2022). Effects of dexmedetomidine on postoperative pain and recovery time in obese patients. Disease Markers, 2022, Article 9715704. https://doi.org/10.1155/2022/9715704

Zhang, X., Leng, Y., Yuan, X., Yang, Y., Zhou, C., & Liu, H. (2025). Efficacy of perioperative dexmedetomidine in postoperative pain and neurocognitive functions in orthopedic surgery: A systematic review and meta-analysis with trial sequential analysis of randomized controlled trials. International Journal of Surgery, 111(5), 3525–3542. https://doi.org/10.1097/JS9.0000000000002315

Zhou, L., Yang, H., Hai, Y., & Cheng, Y. (2022). Perioperative low-dose ketamine for postoperative pain management in spine surgery: A systematic review and meta-analysis of randomized controlled trials. Pain Research and Management, 2022, Article 1507097. https://doi.org/10.1155/2022/1507097

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Published

2026-08-05

How to Cite

Wantania, W. W., & Lalenoh, D. C. (2026). Hemodynamic Stability During Severe Scoliosis Surgery Using A Dexmedetomidine-Based Anesthesia Regimen: A Case Report. Jurnal Sehat Indonesia (JUSINDO), 8(2), 613–622. https://doi.org/10.59141/-.v8i2.540