An Exploratory Study of the Prevalence and Risk Factors of Hypercholesterolemia Among the Elderly in Kelating Village, Tabanan Regency
Keywords:
Hypercholesterolemia, elderly, total cholesterol.Abstract
Hypercholesterolemia, characterized by elevated levels of LDL, triglycerides, and total cholesterol, is a common but often undetected condition among the elderly. In Indonesia, the prevalence of hypercholesterolemia in individuals aged 65–74 is reported at 38.2%. Early detection is critical to prevent severe complications. Dietary habits and physical inactivity, particularly in populations such as the Segara Santhi elderly group in Kerambitan Village, Tabanan—who have a history of pork consumption and low physical activity—may increase vulnerability to this condition. This preliminary cross-sectional study aimed to explore the prevalence and potential risk factors associated with hypercholesterolemia among elderly individuals in the Segara Santhi group. Using purposive random sampling, 30 elderly participants were selected. Fasting total blood cholesterol levels were measured after an 8-hour fast. Data were analyzed and presented descriptively and in tabular form. A total of 16 participants (51.6%) had total cholesterol levels >200 mg/dL, with a higher proportion observed in elderly women. No statistically significant associations (P>0.05) were found between hypercholesterolemia and gender, age, blood pressure, or fasting blood glucose. However, a significant relationship was identified between hypercholesterolemia and uric acid levels (P<0.05). As a preliminary study, these findings suggest a high prevalence of hypercholesterolemia in this elderly population and indicate a possible link with uric acid levels. Further research with a larger sample size is needed to validate these results and better understand associated risk factors.
Downloads
References
Lipsy RJ. The National Cholesterol Education Program Adult Treatment Panel III guidelines. J Manag Care Pharm. 2003;9(1 Suppl):2-5.
Civeira F, Arca M, Cenarro A, Hegele RA. A mechanism-based operational definition and classification of hypercholesterolemia. Journal of Clinical Lipidology. 2022;16(6):813-21.
Pirillo A, Casula M, Olmastroni E, Norata GD, Catapano AL. Global epidemiology of dyslipidaemias. Nat Rev Cardiol. 2021;18(10):689-700.
Kesehatan BPdP. Laporan Nasional Riset Kesehatan Dasar (Riskesdas) 2018. Jakarta: Kementerian Kesehatan Republik Indonesia; 2019.
Ibrahim MA AE, Jialal I. Hypercholesterolemia. Treasure Island (FL): StatPearls Publishing; 2025. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459188/?utm_source=chatgpt.com.
Feingold KR AB, Blackman MR, et al. Introduction to Lipids and Lipoproteins. [Updated 2024 Jan 14]: Endotext [Internet] South Dartmouth (MA); 2024 [Available from: https://www.ncbi.nlm.nih.gov/books/NBK305896/.
Graha KC. Kolesterol. Jakarta: PT Elex Media Komputindo; 2010.
Murray RKG, D. K.; Mayes, P. A.; Rodwell, V. W. Harper's Illustrated Biochemistry. 28th ed. New York: McGraw-Hill Medical; 2009.
Holven KB, Roeters van Lennep J. Sex differences in lipids: A life course approach. Atherosclerosis. 2023;384.
Yeni Rahmawati DDR, Fitri Rahmawati, Elin Perwitasari. HIPERKOLESTEROLEMIA PADA PASIEN LANJUT USIA : STUDI KASUS PUSKESMAS SEYEGAN. Jurnal KEsehatan Tumbusai. 2022.
Fadhil Kurniawan SS, Laila Kamilla. Hubungan Umur, Jenis Kelamin dan Kegemukan dengan Kadar Kolesterol Total Guru SMAN 1 Sei Raya. Journal Laboratorium Khatulistiwa. 2019;Volume 2.
Palmisano BT, Zhu L, Stafford JM. Role of Estrogens in the Regulation of Liver Lipid Metabolism. Adv Exp Med Biol. 2017;1043:227-56.
Renda Pasadena AAA, Wahid Syamsul Hadi. Hubungan Kadar Kolesterol dengan Usia Lanjut dan Jenis Kelamin Pada Pasien Hipertensi di RSUD Nyi Ageng Serang Kulon Progo Journal Pendidikan Tambusai. 2024.
Stapleton PA, Goodwill AG, James ME, Brock RW, Frisbee JC. Hypercholesterolemia and microvascular dysfunction: interventional strategies. J Inflamm (Lond). 2010;7:54.
Trapani L, Pallottini V. Age-Related Hypercholesterolemia and HMG-CoA Reductase Dysregulation: Sex Does Matter (A Gender Perspective). Curr Gerontol Geriatr Res. 2010;2010:420139.
Rita Permatasari ES, Kurniawan Kurniawan. HUBUNGAN KADAR KOLESTEROL TOTAL DENGAN TEKANAN DARAH PADA PASIEN HIPERTENSI PADA USIA ≥ 40 TAHUN. Jurnal Labora Medika. 2022;6.
Wyszyńska J, Łuszczki E, Sobek G, Mazur A, Dereń K. Association and Risk Factors for Hypertension and Dyslipidemia in Young Adults from Poland. Int J Environ Res Public Health. 2023;20(2).
Langitan EJ, Tiho, M., & Purwanto, D. S. Hubungan Kadar Kolesterol Total dengan Kadar Gula Darah Puasa pada Pasien Diabetes Melitus Tipe 2 di RSUD ODSK Provinsi Sulawesi Utara. Health & Medical Sciences. 2025;2.
Hirano T. Pathophysiology of Diabetic Dyslipidemia. J Atheroscler Thromb. 2018;25(9):771-82.
I Gusti Ngurah Bayu Paramartha1 IGBGPP, Sri Ratna Dewi3. Hubungan antara Kadar Asam Urat dengan Profil Lipid pada Pasien Sindrom Koroner Akut di RSUD Sanjiwani Gianyar Aesculapius Medical Journal. 2023;3.
Chen S, Yang H, Chen Y, Wang J, Xu L, Miao M, Xu C. Association between serum uric acid levels and dyslipidemia in Chinese adults: A cross-sectional study and further meta-analysis. Medicine. 2020;99(11):e19088.
Kuwabara M, Borghi C, Cicero AFG, Hisatome I, Niwa K, Ohno M, et al. Elevated serum uric acid increases risks for developing high LDL cholesterol and hypertriglyceridemia: A five-year cohort study in Japan. International Journal of Cardiology. 2018;261:183-8.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 AA Intan Pramesti, Premayani Sidemen, I Made Suma Wirawan, Kadek Nova Adi Putra, Indry Agatha R. P

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under aCreative Commons Attribution-ShareAlike 4.0 International (CC-BY-SA). that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.